Nac for anxiety reddit I wanted to take a more natural approach than… Has anyone else experienced this? I’m 100% sure it’s the NAC. How much should I or do you guys take daily? I see different opinions. Can i take We would like to show you a description here but the site won’t allow us. I have Encephalomyelitis Myalgic and all of my symptoms are part of it but as there is no cure, I have to advocate for my own wellbeing and look for tools that could help me. I pick at my nails uncontrollably and moreso when I feel NAC reduces thought loops for me, I haven't noticed reduction in anxiety but my anxiety is less of a generalized thing and more something that gets triggered. It affects me daily non stop and I can’t get rid of it. Mar 21, 2025 · NAC just stops this, it seems to keep my mind going on a more linear steady pace rather than just getting cut off by some dickhead in traffic and losing my cool, setting the tone for my whole day. If your anxiety stems from the experience that you are not talkative/entertaining enough in social conversations, you might benefit from modafinil. It shows some promising benefits and has very few side-effects [R]. Jul 17, 2024 · N-Acetylcysteine (NAC) has shown promise in the treatment of Obsessive-Compulsive Disorder (OCD), both as an augmentation strategy and monotherapy. Is it really that their anxiety is worse or is it that they just got used to the benefits of the NAC and it went back to the way it was before? I’m not really taking NAC for anxiety but I do have a lot of it and I don’t want to be Hey everyone, I have had extreme anxiety for almost 3 years now that hasn’t gone away. If you have OCD, adding NAC to your treatment plan may help to decrease stress and anxiety. Nac has helped the most for me, I’ve literally had zero anxiety. Im 22 years old and suffering from severe treatment resistant depression, generalized and social anxiety disorder since I was 15. I'm curious why you use NAC/glutathione, and which one works better for you. Leading to overstimulation and autistic symptoms. Never noticed any particular effect on anxiety with NAC. N-acetylcysteine (NAC) is a well-known and safe mucolytic agent, also used in patients with paracetamol overdose. It feels like a stimulant to me. Just posting this for other to find if they experience any bad side effects. There may be some anecdotal reports here that it helped but even reports here on Reddit are less frequent and pronounced in general compared to other things discussed relating to their effect on depression Apr 12, 2025 · 20 Warning about NAC (self. Similar experience this first time I tried nac. Studies have investigated the effectiveness of NAC both as a We would like to show you a description here but the site won’t allow us. From the research that I have done through my school's library, I think that if a person has a dysfunctional glutamatergic system, NAC may be the most readily available treatment option. I've read studies about the benefits of NAC for preventing oxidative damage to the brain and its benefits for the liver, but I haven't heard anything about L-Cysteine excitotoxicity. I was curious if it would do anything for anxiety-related intrusive thoughts and hunger/eating patterns (not something I've ever dealt with but something that she did). Even Valium. Medically it's only used in ranges from 600-1800mg but otherwise people on reddit have great success with for example 2x2g daily. EarthInteresting9781 Thinking about starting on NAC for my anxiety - is there anything I should know beforehand? Find 123 of ratings user reviews and ratings for N-Acetyl Cysteine (NAC) on WebMD including side effects, effectiveness, ease of use and satisfaction. I have been taking NAC daily from January to now with steadily increasing dose ranging from 600mg to Starting the NAC by brand „NOW“ soon, looking for your experiences regarding its effects on social anxiety, sociability, talkativeness, openness and mood. Aug 13, 2025 · NAC is also used by medical professionals to treat serious cognitive disorders like schizophrenia, bipolar disorder, severe depression and anxiety. Two questions I plan on using a supplement daily for social anxiety I’m considering NAC or L-theanine. One is OPC, the other is L-Theanine. Dosage, side effects included. Then i started taking NAC too (started with 800mg and now i'm at 1,200mg) felt much better but i still think it could be better. I read only positive things about NAC (N-Acetyl-Cysteine) for Social Anxiety, depression and other mental or different issues. But I can't seem to find it now. This morning I tried 1500mg at once in the morning. See full list on goodrx. I’m currently not taking any You feel anhedonia because exogenous NAC lowers dopamine. But then I get the cravings again. 2g, i've definitely noticed some anxiety increases when I go off it for a few days afterwards but nothing like you've described. I’ve heard good things about it and how it can treat anxiety in general and reduce stress, but I’m curious about others' experiences with it and if it treated social anxiety symptoms specifically. Positive, seems to improve energy and health. A year and a half later when I had done lots of Cognitive-Behavioral Therapy and my depression/anxiety was greatly reduced, I tired NAC again but this time it just made me feel apathetic. I suggest eating foods which raise NAC naturally instead, ones high in cysteine. Mar 14, 2025 · In addition to its role in these areas, NAC has gained attention for its potential mental health benefits, as research indicates it may help alleviate symptoms of conditions such as depression, anxiety, and obsessive-compulsive disorder (OCD). After achieving my first 30 days of being completely sober thanks to NAC, I slowly start getting anxiety when taking it. Decreasing the dose makes to differences. Most of my adult life has been plagued with social anxiety and general anxiety, especially when driving. Here are the top 9 health benefits of NAC. Discussion and support for sufferers and loved ones with anxiety conditions | discord. I was optimistic and tried it for the first time 2 years ago and noticed a slight increase in my anxiety, so I quit. Jan 16, 2023 · The supplement form of the semi-essential amino acid cysteine, NAC (N-acetyl cysteine) offers benefits such as helping the body create and use protective antioxidants. I’ve known about NACET’s existence for a while, but I’ve never tried it bc the few mentions I saw of it online basically just said it’s a smellier version of NAC that’s slightly more potent. I love its effects on eliminating anxiety and helping with asthma but the negative side effects are horrible. I tried 2 depth psychological therapies, 1 cognitive behavioral therapy and over 13 meds without any success. Which one of them is… To anyone experiencing adverse effects from NAC like heartburn, anxiety, insomnia, heart arrhythmia, itchiness, irritability, brain fog: NAC is supposed to be a strong inhibitor of diamine oxidase, the enzyme that breaks down histamine and other biogenic amines in your gut. For me, it has had a rapid antidepressant effect and has improved a lot of the chronic problems that I've been having such as insomnia, anxiety Jan 12, 2024 · N-acetyl cysteine (NAC) is the supplement form of the amino acid cysteine, which plays several important roles in human health. Also debilitating fatigue and stress (low HRV). I've read studies and a lot of posts here on NAC. I decided to try it again a few weeks ago I had the same happen at a dosage of 2,400mg. 0 negative sides besides maybe your pee smells stronger sometime from the Nac. I take NAC everyday at 1. The protective effect of NAC against lung emphysema is an expected consequence of the decrease in lung senescent-cell accumulation. Your dream will be anxiety free if you take it before sleeping 😄 NAC is energizing and to be taken at morning or mid-day. Hey, sorry for my english. It can help with intrusive thoughts, definitely worth a try but don't expect it to help anxiety on the same level as phenibut or benzos. I already took 600mg of NOW's NAC for I have really bad anxiety and literally nac has helped more than anything ever. My breathing has been checked by many doctors and they all say that I am fine physically. Hi mates, Getting good effects from this supplement. Is there even a difference? L Theanine or NAC for anxiety? Hi guys I keep coming across these 2 supplements for anxiety but I’m hearing mixed reviews. It is the only thing that has provided a semblance of relief for my anxiety, and related excoriation and trichotillomania. In addition to these effects, recent preclinical and clinical studies have shown that NAC exerts beneficial effects on different psychiatric disorders. Basically, title. Been having crazy anxiety lately for maybe the first in my life that I can really remember and decided to give NAC I have been using NAC at 1200mg 2-3 times per day for about a month now. Class of nootropic: GSH enhancer and modulator Derivative of NAC (N-Acetyl-Cysteine) This is probably one of the most powerful compounds i've had the opportunity trying in the last few months minus drugs such as RAD140 (testolone) and Fasoracetam. By reducing oxidative load on the body, excessive intake of NAC can greatly downregulate the KEAP1/NRF-2 endogenous antioxidant pathway. Honestly feel like I'm better with 300-400mg of L-Theanine + Coffee + Nicotine. co . I have had similar symptoms in the past, my blood test showed ‘pre-diabetic’, so borderline. We would like to show you a description here but the site won’t allow us. I also take lots of vitamin c, natural beta carotene, niacin with the flush, B complex Apr 3, 2025 · I've struggled with anxiety and depression for decades and I've been on 150mg Zoloft (I take it woth lunch) and 150mg Trazodone (I take it at night). If I stay off it for a day the anxiety fades and I feel way better. What are your experiences according the dosages of NAC for social 190 votes, 168 comments. I used to take NAC, and I'm not yet sure which is more effective. No We had a lecture last week that discussed use of NAC to manage groups of psychotic patients who had been stratified by the presence of redox dysfunction in blood tests, showing positive results. So I have taken an interest in the benefits of glutathione lately, and I’m trying to understand the difference between supplementing glutathione vs supplementing NAC to boost glutathione production levels. Personally I found that two substances had a calming effect on me. Jul 29, 2024 · Explore N-Acetylcysteine's potential benefits for anxiety and OCD, including mechanisms, dosages, and personal success stories. This dosage knocks out my anxiety and depression but I am unable to feel joy, I just want to get stuff done. 29 votes, 96 comments. I have ADHD and I'm slightly and alcohoolic (I'm having 4-5 drinks every night). Anyone else used nac for this? What were your results? any problems long term? Thanks! peace Any Experiences with NAC for treating social anxiety symptoms? So I’ve been looking into ordering some. Plus a coffee a day. trueTook NAC for second day now - 600mg in the morning. I typically take magnesium, black seed oil, and a b vitamin on the daily. com Unlock the potential of N-Acetyl Cysteine (NAC) for anxiety relief. I now found NAC can help people with mental illness, especially depression, anxiety and cognition. It's the age old debate. 3 of 7 days of the week, I take 1200 mg of N-Acetyl Cysteine & honestly I find myself feeling more calm, less irritable, and better able to control my anger than days where I don’t take it. N-acetyl cysteine (NAC) is a glutamate . Posted October 31, 2018 | Reviewed by Ekua Hagan Obsessive compulsive and related disorders are a collection of debilitating psychiatric disorders in which the role of glutamate dysfunction in the underpinning neurobiology is becoming well established. I've been struggling with anxiety and with some OCD symptoms for the last 6 months (intrusive thoughts and etc). - Am on prescription medications for those issues. I don't know where it started, but I've never found anything that actually tames my anxiety, rather most substances have only masked it in a very unsustainable way. I am suffering with brain fog, a pressure that is likely inflammation in my brain and lack of blood flow and for now there is no much help from doctors. NAC and Taurine ? Just wondering okay to add NAC to my daily regimen. I just want it gone but I’m Discussion and support for sufferers and loved ones with anxiety conditions | discord. I've recently tried NAC for OCD and anxiety. Posted October 31, 2018 | Reviewed by Ekua Hagan We would like to show you a description here but the site won’t allow us. But I don't recognize any big effects on my depression or social anxiety even if I'm taking it for more than 1 1/2 months daily now in that dose. Recently i’ve been having irritability issues and NAC has helped calmed me. I just tried NAC for the second time and it fucked me up yet again. I pair it with taurine and glycine and that helps my social anxiety substantially. Makes me super restless and anxious for the entire day. Currently trying liposomal glutathione for anxiety (OCD, specifically). Aug 13, 2020 · The first clinical use of NAC was in the 1960s for cystic fibrosis. This would not necessarily be bad if all that NRF-2 did was handle oxidative load, but it turns out it is a signal There have also been studies showing NAC may be helpful/reduce OCD tendencies in OCD-associated conditions such as trichotollimania (hair-pulling) and in uncontrollable skin/nail picking/biting. When I was still using nicotine, after a few weeks the NAC seemed to put me in a bad mood, even if it still stopped the thought loops. Discussion on using NAC for managing intrusive thoughts, ROCD, OCD, anxiety, and fear of loss, including dosage advice and experiences from users. I have hardcore OCD and lots of anxiety of course and my… I’m not super knowledgeable about how NAC works in the brain, but the majority of posts I’ve seen on Reddit claim that it’s amazing for anxiety and obsessive thoughts, which I’ve been dealing with for as long as I can remember. This wired feeling i get from it subsides in the evening but doesn’t go away and causes sleep problems. Experienced shortness of breath and anxiety. I started taking L-Theanine (200-400mg daily), felt a little bit better but still not enough. Mar 17, 2024 · Full review of NAC, is a powerful antioxidant protects nerves & helps reduce anxiety, OCD, and depression. Tuesday - took 500mg in morning and 500mg at night. No recognizeable effects or changes either. NAC, accidentally started taking it when I had Covid to clear congestion and then noticed my physical anxiety and OCD was significantly reduced with really improved sleep. In the 1970s, its efficacy for the treatment of paracetamol overdose was discovered. It protects the liver for the same reason it protects the brain: it works as a powerful antioxidant, boosting levels of the body’s own primary antioxidant—glutathione. I take 3x500mg NAC (N-Acetyl-Cysteine) as I heard it helps liver, depression, anxiety and so much more. This role seems independent from antioxidant gene expression, since opposite variations in antioxidant enzyme expression were seen in healthy mice and JunD–/– mice during aging. Context: - History of severe anxiety and depression. Supplements) submitted 3 hours ago by squatch95 I’ve been trying to utilize NAC the past few months for rumination/ocd like symptoms and some anxiety support. Problem is I was basically anxiety and depression free, but my anxiety has returned (not as strong as before) a few months ago. . I can’t even breath correctly. All issues of mine. L-theanine works like 6-8 hours only. Oct 31, 2018 · Psychiatry NAC: The Amino Acid That Turns Psychiatry on Its Head Research on N-acetylcysteine (NAC) illuminates an old question. She wants me to try this before adding another medication. I really find taurine helps with my anxiety , I usually take two to three grams a day but would love to add NAC for a few months as well. Altering Oct 31, 2018 · Psychiatry NAC: The Amino Acid That Turns Psychiatry on Its Head Research on N-acetylcysteine (NAC) illuminates an old question. 12 votes, 31 comments. So far, I've only taken it 2 times. I recently tried ashwagandha - it reduced stress and helped me feel more calm, however my motivation dropped (no urgency to do much, especially at work). My psychiatrist told me to take 600mg of NAC, and I'm on day 4. I already took 600mg of NOW's NAC for We would like to show you a description here but the site won’t allow us. Although inconsistent, NAC can still be considered useful for obsessive-compulsive disorders according to a large review. How does N-Acetyl L-Cysteine work in the Brain? I’ve heard a handful of people who take NAC for anxiety say it helps them a lot but when they get off the supplement they rebound with worse anxiety than ever. Im suspecting that my glutamate/gaba-balance has been way off for a long time. Many potential mechanisms have been proposed to underlie the therapeutic effects of NAC, including the regulation of several Aug 18, 2020 · NAC is short for n-acetylcysteine. Now I know I shouldn’t take NAC every single day, as I know how it can be harmful, so how do most of you cycle NAC can lead to demotivation and anhedonia in some people so may not be great for your specific needs. 58 votes, 99 comments. Since then, a great number of applications have been attributed to NAC mainly due to its implication in oxidative stress. NAC has a very powerful sulfur group that is good at breaking down the disulfide bonds holding together mucus making it a powerful mucolytic. 15 votes, 54 comments. Primarily through its antioxidant, anti-inflammatory, and glutamate modulation activity, NAC has been investigated in the treatment of neurodevelopmental disorders, schizophrenia spectrum disorders, bipolar-related disorders, depressive disorders, anxiety disorders, obsessive If you continue to have issues falling asleep it is probably due to the histamine released by NAC as it breaks down. Usually I was taking ashwaganda, l-Theanine, magnesium. I think I remember reading online that there was some reason they don't work well together. Is there any reason to use NACET over plain ol’ NAC? I usually take 1 gram of NAC 2x per day to help with inflammation and reduction of anxiety/OCD Only problem with NAC is high dose use or long term use can cause pretty moderate rebound anxiety and “withdrawal” from glutamate rebound. They had groups taking NAC for 12 weeks and found that after the 12 weeks, the urge to partake in these behaviors decreased significantly. Monday - took 500mg nothing different, heartrate was a bit elevated. Thus I guess NAC should be treated as a medicine (as it initially was) not like a supplement. There's not really any strong evidence for its use regarding depression and anxiety. There’s A LOT of reports about it on Reddit. You may also feel a bit of anxiety with continued use, you may not. Oct 4, 2019 · Our results therefore support a direct role for NAC in tumor initiation. I take 600 in the morning with breakfast. Increasing doesn't do either. Anecdotally: I started NAC about a year ago and my wife was curious about it. It’s been so terrible and has caused severe depression as I feel like I’m suffering daily. The potential drawbacks are related to the fact that a number of mechanisms in our bodies are regulated by challenge and feedback loops. The physical symptoms of anxiety were greatly decreased when I took NAC, which allowed me to devote more energy toward resisting compulsions and recognizing cognitive distortions. NAC and oxidative stress Reactive We would like to show you a description here but the site won’t allow us. in general it's the best supplement i've ever taken but i've been taking it for the past 6+ months and have been experiencing severe loss of pleasure in things Reply reply NorthOfMyLungs • Sometimes, anxiety has a physical cause, and it may be worth getting some blood samples taken to rule anything out. Recent studies suggest potential implications of NAC in several psychiatric disorders. Didn't think much of it as I drank the night before. What should I do? Cut dose in half? Do it every other night? Oct 17, 2019 · N-acetylcysteine (NAC) is an amino acid widely used in emergency rooms to treat people who overdose on acetaminophen (Tylenol™). Can't say for sure but had some anxiety today. Not like an extreme calming sensation, but I feel a noticeable difference. Woke up during the night with chest tightness and discomfort and shortness of breath but went away Anyone tried NAC for anxiety? My psychiatrist told me to try the supplement NAC for my anxiety/ OCD tendencies. Have a few other nootropics in the mix I use a few times a week for work. Libido was also reduced a good amount from using it. My friend that is a chronic over thinker, worrier and has a history of short term drug use was getting anxiety attacks because of NAC. Took 1000mg and lowkey felt horrible - headache, groggy, just totally out of it. Many potential mechanisms have bee … NAC can help with anxiety and recovering from viral infections but should be cycled. - Added in NAC at a… 66 votes, 165 comments. Curious, I saw it listed on bromantane. From what I’ve gathered, glutathione is not all that absorbable, unless you find one of the expensive liposomal versions. I looked into some of the literature on NAC - and there is a surprising number of RCTs and meta-analyses showing pretty convincing benefit for MDD, general psychopathology and cognition in We would like to show you a description here but the site won’t allow us. Discover how N-Acetyl Cysteine (NAC) can help you overcome anxiety and improve your mental well-being in this comprehensive guide. I get efficacy taking it PO but there are also Rx inhaled versions for COPD and Tuberculosis associated mucus plugging. It’s almost seemed to make it all worse. you name it. gg/r-anxiety | Please look over the rules before posting to the subreddit We would like to show you a description here but the site won’t allow us. I take it with L-theanine 400mg and L-Tyrosine 500mg. Here‘s a study I found of one patient who didn‘t respond to antidepressants was having success by adding NAC: Abstract N -acetyl-L-cysteine (NAC) is a compound of increasing interest in the treatment of psychiatric disorders. Started a month ago, took a break from it, then started again. Palpitations are probably due to mineral deficiency which NAC can lead to so if you take it, you need to supplement with a multi and trace minerals. Does NAC work for social anxiety and asthma? I have taken Nac 600mgs, silymarin and Liver care from himalaya on and off together for atleast a decade in the morning with my coffee and up to 2 more times a day on an empty stomach. Explore effective strategies to enhance your mental health today. I'm going to take a break from NAC,. It might be worth a try though, because in my experience, it is the only thing to help my anxiety that stops my intrusive thoughts and overthinking without altering my mind or causing rebound effects. Mar 24, 2021 · N -acetylcysteine (NAC) is a well-known and safe mucolytic agent, also used in patients with paracetamol overdose. porec drxvkps ruvex bbd xsdw fnyuyzz nctxxez upfd mwxig stissr acf usqtbthu gfpwzk qga uimli